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Article

A population-level statistic for assessing Mendelian behavior of genotyping-by-sequencing data from highly duplicated genomes.

BMC bioinformatics - 22 Mar 2022

Clark Lindsay V, Mays Wittney, Lipka Alexander E, Sacks Erik J

Abstract excerpt

BACKGROUND: Given the economic and environmental importance of allopolyploids and other species with highly duplicated genomes, there is a need for methods to distinguish paralogs, i.e. duplicate sequences within a genome, from Mendelian loci, i.e. single copy sequences that pair at meiosis. The ratio of observed to expected heterozygosity is an effective tool for filtering loci but requires genotyping to be...

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Identifiers

PMID: 35317727
DOI: 10.1186/s12859-022-04635-9
PMCID: PMC8939213

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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