Article
Serotonin 2A receptor gene (HTR2A) polymorphism in alcohol-dependent patients.
Pharmacological reports : PR - 1 Jan 2012
Wrzosek Małgorzata, Jakubczyk Andrzej, Wrzosek Michał, Matsumoto Halina, Łukaszkiewicz Jacek, Brower Kirk J, Wojnar Marcin
Abstract excerpt
BACKGROUND: The serotonergic (5-HT) dysfunction has been frequently described in subjects with alcohol dependence (AD). In the present study, a potential relationship between T102C polymorphism in the 5-HT receptor subtype 2Agene (HTR2A) and alcohol dependence was examined. METHODS: Genotypes were analyzed in 150 AD patients diagnosed with DSM-IV criteria and in 80 healthy controls. RESULTS: The genetic analysis...
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