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Article

Object recognition as a measure of memory in 1-2 years old transgenic minipigs carrying the APPsw mutation for Alzheimer's disease.

Transgenic research - 1 Dec 2012

Søndergaard Lene Vammen, Ladewig Jan, Dagnæs-Hansen Frederik, Herskin Mette S, Holm Ida Elisabeth

Abstract excerpt

Alzheimer's disease (AD) is a disabling, fatal disease, where animal models potentially can enable investigation of aetiology and treatment. The first litter of Göttingen minipigs carrying a mutation for human AD was born in 2007, showing transgene expression. In human AD patients, memory impairment is the most striking and consistent feature. The aim of the present study was to examine effects of the APPsw...

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PMID: 22661126
DOI: 10.1007/s11248-012-9620-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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