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Article

Differential regulation of embryonic and adult β cell replication

1 Jul 2012

Abstract excerpt

Diabetes results from an inadequate functional β cell mass, either due to autoimmune destruction (Type 1 diabetes) or insulin resistance combined with β cell failure (Type 2 diabetes). Strategies to enhance β cell regeneration or increase cell proliferation could improve outcomes for patients with diabetes. Research conducted over the past several years has revealed that factors regulating embryonic β cell mass...

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PMID: 22659844
DOI: 10.4161/cc.20545

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