Article
Genetic susceptibility to teratogens: state of the art.
Reproductive toxicology (Elmsford, N.Y.) - 1 Sept 2012
Cassina Matteo, Salviati Leonardo, Di Gianantonio Elena, Clementi Maurizio
Abstract excerpt
There is evidence that the susceptibility to the teratogenic effect of drugs within human populations varies extremely from one individual to another, even after identical exposures. One of the factors that may explain these interindividual differences is the genetic makeup in the pharmacokinetics and pharmacodynamics of the respective drugs. In fact, both maternal and embryonic/fetal genotypes can affect...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
