Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Factors contributing to interindividual variability to chemical toxicity].

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke - 28 Feb 2002

Lindeman Birgitte, Søderlund Erik J, Dybing Erik

Abstract excerpt

Recognising toxicokinetic and toxicodynamic variability is important in the risk assessment of chemicals and may help to explain individual differences in susceptibility in exposed populations. This presentation discusses the influence of age, gender, disease and genetics on toxicokinetic and toxicodynamic processes. Neonates have a reduced capacity for metabolism and elimination of xenobiotics that may enhance...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug-Related Side Effects and Adverse Reactions
Share to Drug Resistance

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gastrointestinal Diseases

Share to Kidney Diseases

Share to Liver Diseases

Share to Pharmacogenetics

Share to Pharmacokinetics

Share to Sex Factors

Source

Identifiers

PMID: 11998714

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Factors contributing to interindividual variability to chemical toxicity].PMID 11998714Read ↗

Heterogeneity of toxicant response: sources of human variability.Semantic proximity Read ↗

The relevance of xenobiotic metabolism in the interindividual susceptibility to chemicals.Semantic proximity Read ↗

Sex Differences in NeurotoxicogeneticsSemantic proximity Read ↗

Genetic variability in susceptibility and response to toxicants.Semantic proximity Read ↗

Genetic basis of toxic reactions to drugs and chemicals.Semantic proximity Read ↗

Toxicogenomics and clinical toxicology: an example of the connection between basic and applied sciences.Semantic proximity Read ↗

[Genetic variations in the metabolism of environmental toxins].Semantic proximity Read ↗

[Pharmacologic and toxicologic results in genetic polymorphisms (review)].Semantic proximity Read ↗

Genetic susceptibility to adverse effects of drugs and environmental toxicants. The role of the CYP family of enzymes.Semantic proximity Read ↗

[Interindividual differences in efficacy and toxicity induced by therapeutic drugs and xenobiotics in relation to genetic polymorphisms in xenobiotic metabolizing enzymes].Semantic proximity Read ↗

Biochemical individuality: the next generation.Semantic proximity Read ↗

Pharmacogenetics, pharmacogenomics and ecogenetics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.