Article
Primary mesenchymal stem and progenitor cells from bone marrow lack expression of CD44 protein.
The Journal of biological chemistry - 27 Jul 2012
Qian Hong, Le Blanc Katarina, Sigvardsson Mikael
Abstract excerpt
Despite significant progress in our understanding of mesenchymal stem cell (MSC) biology during recent years, much of the information is based on experiments using in vitro culture-selected stromal progenitor cells. Therefore, the natural cellular identity of MSCs remains poorly defined. Numerous studies have reported that CD44 expression is one of the characteristics of MSCs in both humans and mice; however, we...
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