Article
Phenotypic and functional heterogeneity of human bone marrow- and amnion-derived MSC subsets.
Annals of the New York Academy of Sciences - 1 Aug 2012
Sivasubramaniyan Kavitha, Lehnen Daniela, Ghazanfari Roshanak, Sobiesiak Malgorzata, Harichandan Abhishek, Mortha Elisabeth, Petkova Neli, Grimm Sabrina, Cerabona Flavianna, de Zwart Peter, Abele Harald, Aicher Wilhelm K, Faul Christoph, Kanz Lothar, Bühring Hans-Jörg
Abstract excerpt
Bone marrow-derived mesenchymal stromal/stem cells (MSCs) are nonhematopoietic cells that are able to differentiate into osteoblasts, adipocytes, and chondrocytes. In addition, they are known to participate in niche formation for hematopoietic stem cells and to display immunomodulatory properties. Conventionally, these cells are functionally isolated from tissue based on their capacity to adhere to the surface of...
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