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Article

Low/negative expression of PDGFR-α identifies the candidate primary mesenchymal stromal cells in adult human bone marrow.

Stem cell reports - 9 Dec 2014

Li Hongzhe, Ghazanfari Roshanak, Zacharaki Dimitra, Ditzel Nicholas, Isern Joan, Ekblom Marja, Méndez-Ferrer Simón, Kassem Moustapha, Scheding Stefan

Abstract excerpt

Human bone marrow (BM) contains a rare population of nonhematopoietic mesenchymal stromal cells (MSCs), which are of central importance for the hematopoietic microenvironment. However, the precise phenotypic definition of these cells in adult BM has not yet been reported. In this study, we show that low/negative expression of CD140a (PDGFR-α) on lin(-)/CD45(-)/CD271(+) BM cells identified a cell population with...

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Identifiers

PMID: 25454633
DOI: 10.1016/j.stemcr.2014.09.018
PMCID: PMC4264066

Genes

MSC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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