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Article

FOXO1 in the ventromedial hypothalamus regulates energy balance.

The Journal of clinical investigation - 1 Jul 2012

Kim Ki Woo, Donato Jose, Berglund Eric D, Choi Yun-Hee, Kohno Daisuke, Elias Carol F, Depinho Ronald A, Elmquist Joel K

Abstract excerpt

The transcription factor FOXO1 plays a central role in metabolic homeostasis by regulating leptin and insulin activity in many cell types, including neurons. However, the neurons mediating these effects and the identity of the molecular targets through which FOXO1 regulates metabolism remain to b...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22653058
DOI: 10.1172/JCI62848
PMCID: PMC3386826

Genes

FOXO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22653058-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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