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Article

Splice variant PRKC-ζ(-PrC) is a novel biomarker of human prostate cancer.

British journal of cancer - 10 Jul 2012

Yao S, Ireland S J, Bee A, Beesley C, Forootan S S, Dodson A, Dickinson T, Gerard P, Lian L-Y, Risk J M, Smith P, Malki M I, Ke Y, Cooper C S, Gosden C, Foster C S

Abstract excerpt

BACKGROUND: Previously, using gene-knockdown techniques together with genome expression array analysis, we showed the gene protein Kinase C (PKC)-zeta (PRKCZ) to mediate the malignant phenotype of human prostate cancer. However, according to NCBI, the gene has undergone several major iterations. Therefore, to understand the relationship between its structure and biological activities, we have analysed its...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22644296
DOI: 10.1038/bjc.2012.162
PMCID: PMC3394965

Genes

PRKCZ

Provenance

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