Article
HIV-specific immune dysregulation and atherosclerosis.
Current HIV/AIDS reports - 1 Sept 2012
Zanni Markella V, Grinspoon Steven K
Abstract excerpt
HIV + patients face a heightened risk of cardiovascular disease (CVD), which cannot be fully explained by traditional risk factors or antiretroviral therapy (ART)-related cardiotoxicity. Increasing evidence suggests a significant contribution of HIV-specific immune dysregulation to atherosclerosis. HIV-specific immune dysregulation may have the following atherogenic effects: 1) activation of endothelial and...
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