Article
Genetic variants of CD209 associated with Kawasaki disease susceptibility.
PloS one - 1 Jan 2014
Kuo Ho-Chang, Huang Ying-Hsien, Chien Shu-Chen, Yu Hong-Ren, Hsieh Kai-Sheng, Hsu Yu-Wen, Chang Wei-Chiao
Abstract excerpt
BACKGROUND: Kawasaki disease (KD) is a systemic vasculitis with unknown etiology mainly affecting children in Asian countries. Dendritic cell-specific intercellular adhesion molecule-3 grabbing non-integrin (DC-SIGN, CD209) in humans was showed to trigger an anti-inflammatory cascade and associated with KD susceptibility. This study was conducted to investigate the association between genetic polymorphisms of...
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