Article
Interferon-gamma Genetic Polymorphism and Expression in Kawasaki Disease.
Medicine - 1 Apr 2016
Huang Ying-Hsien, Hsu Yu-Wen, Lu Hsing-Fang, Wong Henry Sung-Ching, Yu Hong-Ren, Kuo Hsing-Chun, Huang Fu-Chen, Chang Wei-Chiao, Kuo Ho-Chang
Abstract excerpt
Kawasaki disease (KD) is a systemic vasculitis of unknown etiology. IFNG gene encoding interferon (IFN)-γ, produced by natural killer cells and T cells, has been suggested to play an important role in the immunopathogenesis of Kawasaki disease. The aim of this study was to examin the correlation of gene polymorphisms of the IFNG gene and plasma levels of IFN-γ in KD patients and their outcomes.A total of 950...
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