Base excision repair pathway: PARP1 genotypes as modulators of therapy response in cervical cancer patients.

doi:10.1080/1354750X.2016.1204006

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Base excision repair pathway: PARP1 genotypes as modulators of therapy response in cervical cancer patients.

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 Feb 2017

Nogueira Augusto, Assis Joana, Faustino Ilda, Pereira Deolinda, Catarino Raquel, Medeiros Rui

Abstract excerpt

CONTEXT: Genetic polymorphisms in genes of the base excision repair (BER) pathway appear to modulate the therapy response of cancer patients. PARP1 protein recognizes the DNA strand damage and facilitates the subsequent recruitment of BER proteins. Few studies have reported an association between PARP1 Val762Ala polymorphism (rs1136410) and cancer therapy response. OBJECTIVE: The purpose of our study was to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Predictive Value of Tests

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cisplatin

Share to DNA Repair

Share to Poly (ADP-Ribose) Polymerase-1

Share to Radiotherapy

Share to Survival Analysis

Share to Treatment Outcome

Share to Uterine Cervical Neoplasms

Source

Open in PubMed

Identifiers

PMID: 27323894
DOI: 10.1080/1354750X.2016.1204006

Genes

PARP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Base excision repair pathway: PARP1 genotypes as modulators of therapy response in cervical cancer patients.PMID 27323894Read ↗

Involvement of PARP-1 Val762Ala polymorphism in the onset of cervical cancer in caucasian women.Semantic proximity Read ↗

PARP-1 Val762Ala polymorphism is associated with risk of cervical carcinoma.Semantic proximity Read ↗

PARP-1 Val762Ala polymorphism and risk of cancer: a meta-analysis based on 39 case-control studies.Semantic proximity Read ↗

A functional polymorphism in the poly(ADP-ribose) polymerase-1 gene increases the risk of endometrial carcinoma.Semantic proximity Read ↗

A polymorphism in the base excision repair gene PARP2 is associated with differential prognosis by chemotherapy among postmenopausal breast cancer patients.Semantic proximity Read ↗

Association between PARP-1 V762A polymorphism and cancer susceptibility: a meta-analysis.Semantic proximity Read ↗

DNA glycosylases involved in base excision repair may be associated with cancer risk in BRCA1 and BRCA2 mutation carriers.Semantic proximity Read ↗

Association between the PARP1 Val762Ala polymorphism and cancer risk: evidence from 43 studies.Semantic proximity Read ↗

Understanding Role of DNA Repair and Cytochrome p-450 Gene Polymorphisms in Cervical Cancer Patient Treated With Concomitant Chemoradiation.Semantic proximity Read ↗

A functional polymorphism in the poly(ADP-ribose) polymerase-1 gene is associated with platinum-based chemotherapeutic response and prognosis in epithelial ovarian cancer patients.Semantic proximity Read ↗

Polymorphisms in the base excision repair pathway modulate prognosis of platinum-based chemotherapy in advanced non-small cell lung cancer.Semantic proximity Read ↗

PARP1 rs1136410 Val762Ala contributes to an increased risk of overall cancer in the East Asian population: a meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.