Article
Exploratory analysis of candidate germline gene polymorphisms in breast cancer patients treated with neoadjuvant anthracycline-containing chemotherapy and associations with febrile neutropenia.
Pharmacogenomics - 1 Jan 2015
Charehbili A, de Groot S, van der Straaten T, Swen J J, Pijl H, Gelderblom H, van de Velde C J H, Nortier J W R, Guchelaar H J, Kroep J R
Abstract excerpt
AIM: SNPs may be associated with (side) effects of chemotherapy and may be useful as biomarkers to predict febrile neutropenia. PATIENTS & METHODS: 187 DNA samples extracted from formalin-fixed paraffin-embedded tissue from patients with stage II/III HER2-negative breast cancer were genotyped. RESULTS: Candidate SNPs were selected and explored for association with febrile neutropenia and/or pathological complete...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.