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Validation of inflammatory genetic variants associated with long-term cancer related fatigue in a large breast cancer cohort.

Brain, behavior, and immunity - 1 Oct 2018

Kühl T, Behrens S, Jung A Y, Obi N, Thöne K, Schmidt M E, Becher H, Chang-Claude J

Abstract excerpt

BACKGROUND: Studies to date have reported several associations between single nucleotide polymorphisms (SNPs) and cancer related fatigue (CRF), but have been limited by small sample sizes, missing adjustment for relevant covariates or multiple testing, as well as varying CRF definitions, i.e. time and method of assessment. This study aimed to validate previously reported associations using the largest independent...

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PMID: 29763737
DOI: 10.1016/j.bbi.2018.05.009

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