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Article

An Epstein-Barr Virus (EBV) mutant with enhanced BZLF1 expression causes lymphomas with abortive lytic EBV infection in a humanized mouse model.

Journal of virology - 1 Aug 2012

Ma Shi-Dong, Yu Xianming, Mertz Janet E, Gumperz Jenny E, Reinheim Erik, Zhou Ying, Tang Weihua, Burlingham William J, Gulley Margaret L, Kenney Shannon C

Abstract excerpt

Immunosuppressed patients are at risk for developing Epstein-Barr Virus (EBV)-positive lymphomas that express the major EBV oncoprotein, LMP1. Although increasing evidence suggests that a small number of lytically infected cells may promote EBV-positive lymphomas, the impact of enhanced lytic gen...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22623780
DOI: 10.1128/JVI.00770-12
PMCID: PMC3421695

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22623780-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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