Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Some strains of Plasmodium falciparum, a human malaria parasite, evade the complement-like system of Anopheles gambiae mosquitoes.

Proceedings of the National Academy of Sciences of the United States of America - 10 Jul 2012

Molina-Cruz Alvaro, DeJong Randall J, Ortega Corrie, Haile Ashley, Abban Ekua, Rodrigues Janneth, Jaramillo-Gutierrez Giovanna, Barillas-Mury Carolina

Abstract excerpt

Plasmodium falciparum lines differ in their ability to infect mosquitoes. The Anopheles gambiae L3-5 refractory (R) line melanizes most Plasmodium species, including the Brazilian P. falciparum 7G8 line, but it is highly susceptible to some African P. falciparum strains such as 3D7, NF54, and GB4. We investigated whether these lines differ in their ability to evade the mosquito immune system. Silencing key...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anopheles
Share to Complement System Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Crosses, Genetic

Share to Immune System

Share to Insect Proteins

Share to Malaria

Share to Plasmodium falciparum

Share to RNA, Double-Stranded

Source

Open in PubMed Open full text

Identifiers

PMID: 22623529
DOI: 10.1073/pnas.1121183109
PMCID: PMC3396512

Genes

TEP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Some strains of Plasmodium falciparum, a human malaria parasite, evade the complement-like system of Anopheles gambiae mosquitoes.PMID 22623529Read ↗

Mosquito immune responses and compatibility between Plasmodium parasites and anopheline mosquitoesSemantic proximity Read ↗

Late-phase immune responses limiting oocyst survival are independent of TEP1 function yet display strain specific differences in Anopheles gambiae.Semantic proximity Read ↗

Transmission Blocking Immunity in the Malaria Non-Vector Mosquito Anopheles quadriannulatus Species ASemantic proximity Read ↗

A genetic study of a melanization response to Sephadex beads in Plasmodium-refractory and -susceptible strains of Anopheles gambiae.Semantic proximity Read ↗

Quantitative trait loci for refractoriness of Anopheles gambiae to Plasmodium cynomolgi B.Semantic proximity Read ↗

A genetic module regulates the melanization response of Anopheles to Plasmodium.Semantic proximity Read ↗

Immune Regulation of Plasmodium Is Anopheles Species Specific and Infection Intensity DependentSemantic proximity Read ↗

Variation in susceptibility of African Plasmodium falciparum malaria parasites to TEP1 mediated killing in Anopheles gambiae mosquitoes.Semantic proximity Read ↗

A shared genetic mechanism for melanotic encapsulation of CM-Sephadex beads and a malaria parasite, Plasmodium cynomolgi B, in the mosquito, Anopheles gambiae.Semantic proximity Read ↗

Genetic clonality of Plasmodium falciparum affects the outcome of infection in Anopheles gambiae.Semantic proximity Read ↗

Plasmodium gallinaceum: a refractory mechanism of ookinete killing in the mosquito, Anopheles gambiae.Semantic proximity Read ↗

The JNK Pathway Is a Key Mediator of Anopheles gambiae Antiplasmodial ImmunitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.