Article
Quantitative trait loci for refractoriness of Anopheles gambiae to Plasmodium cynomolgi B.
Science (New York, N.Y.) - 18 Apr 1997
Zheng L, Cornel A J, Wang R, Erfle H, Voss H, Ansorge W, Kafatos F C, Collins F H
Abstract excerpt
The severity of the malaria pandemic in the tropics is aggravated by the ongoing spread of parasite resistance to antimalarial drugs and mosquito resistance to insecticides. A strain of Anopheles gambiae, normally a major vector for human malaria in Africa, can encapsulate and kill the malaria parasites within a melanin-rich capsule in the mosquito midgut. Genetic mapping revealed one major and two minor...
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