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Article

A genetic study of a melanization response to Sephadex beads in Plasmodium-refractory and -susceptible strains of Anopheles gambiae.

The American journal of tropical medicine and hygiene - 1 Apr 1997

Gorman M J, Paskewitz S M

Abstract excerpt

A previously selected Plasmodium-refractory strain of Anopheles gambiae melanotically encapsulates many species of Plasmodium. Genetic studies of this strain have shown that this refractory phenotype is controlled by a limited number of genes, and the existence of two such genes, Pif-B and Pif-C, has been demonstrated. Further work to determine the molecular basis for this mode of refractoriness led to the...

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PMID: 9158056
DOI: 10.4269/ajtmh.1997.56.446

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