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Article

A genetic module regulates the melanization response of Anopheles to Plasmodium.

Cellular microbiology - 1 Sept 2006

Volz Jennifer, Müller Hans-Michael, Zdanowicz Agnieszka, Kafatos Fotis C, Osta Mike A

Abstract excerpt

Two modes of refractoriness to Plasmodium, ookinete lysis and melanization, are known in the malaria vector, Anopheles gambiae. Melanization, a potent insect immune response, is manifested in a genetically selected refractory strain and in susceptible mosquitoes that are depleted of specific C-type lectins (CTLs). Here we use a systematic in vivo RNA interference-mediated reverse genetic screen and other recent...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16922859
DOI: 10.1111/j.1462-5822.2006.00718.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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