Article
Genetic clonality of Plasmodium falciparum affects the outcome of infection in Anopheles gambiae.
International journal for parasitology - 15 May 2012
Nsango Sandrine E, Abate Luc, Thoma Martine, Pompon Julien, Fraiture Malou, Rademacher Annika, Berry Antoine, Awono-Ambene Parfait H, Levashina Elena A, Morlais Isabelle
Abstract excerpt
Mosquito infections with natural isolates of Plasmodium falciparum are notoriously variable and pose a problem for reliable evaluation of efficiency of transmission-blocking agents for malaria control interventions. Here, we show that monoclonal P. falciparum isolates produce higher parasite loads than mixed ones. Induction of the mosquito immune responses by wounding efficiently decreases Plasmodium numbers in...
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