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Article

A revisited folding reporter for quantitative assay of protein misfolding and aggregation in mammalian cells.

Biotechnology journal - 1 Oct 2012

Gregoire Simpson, Kwon Inchan

Abstract excerpt

Protein misfolding and aggregation play important roles in many physiological processes. These include pathological protein aggregation in neurodegenerative diseases and biopharmaceutical protein aggregation during production in mammalian cells. To develop a simple non-invasive assay for protein misfolding and aggregation in mammalian cells, the folding reporter green fluorescent protein (GFP) system, originally...

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Identifiers

PMID: 22623352
DOI: 10.1002/biot.201200103
PMCID: PMC3517142

Genes

SOD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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