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Derivation and cardiomyocyte differentiation of induced pluripotent stem cells from heart failure patients

22 May 2012

Abstract excerpt

AIMS: Myocardial cell replacement therapies are hampered by a paucity of sources for human cardiomyocytes and by the expected immune rejection of allogeneic cell grafts. The ability to derive patient-specific human-induced pluripotent stem cells (hiPSCs) may provide a solution to these challenges. We aimed to derive hiPSCs from heart failure (HF) patients, to induce their cardiomyocyte differentiation, to...

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PMID: 22621821
DOI: 10.1093/eurheartj/ehs096

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