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Article

WAVE2-Abi2 complex controls growth cone activity and regulates the multipolar-bipolar transition as well as the initiation of glia-guided migration.

Cerebral cortex (New York, N.Y. : 1991) - 1 Jun 2013

Xie Min-Jue, Yagi Hideshi, Kuroda Kazuki, Wang Chen-Chi, Komada Munekazu, Zhao Hong, Sakakibara Akira, Miyata Takaki, Nagata Koh-Ichi, Oka Yuichiro, Iguchi Tokuichi, Sato Makoto

Abstract excerpt

Glia-guided migration (glia-guided locomotion) during radial migration is a characteristic yet unique mode of migration. In this process, the directionality of migration is predetermined by glial processes and not by growth cones. Prior to the initiation of glia-guided migration, migrating neurons transform from multipolar to bipolar, but the molecular mechanisms underlying this multipolar-bipolar transition and...

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PMID: 22617848
DOI: 10.1093/cercor/bhs123

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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