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Article

Clinical Considerations of<i>BRCA1</i>- and<i>BRCA2</i>-Mutation Carriers: A Review

1 Jan 2011

Abstract excerpt

Individuals who carry an inherited mutation in the breast cancer 1 (BRCA1) and BRCA2 genes have a significant risk of developing breast and ovarian cancer over the course of their lifetime. As a result, there are important considerations for the clinician in the counseling, followup and management of mutation carriers. This review outlines salient aspects in the approach to patients at high risk of developing...

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PMID: 22312502
DOI: 10.1155/2011/374012

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