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Article

Solution structures of human transforming growth factor alpha derived from 1H NMR data.

Biochemistry - 28 Aug 1990

Kline T P, Brown F K, Brown S C, Jeffs P W, Kopple K D, Mueller L

Abstract excerpt

The 600-MHz 1H NMR spectrum of the des-Val-Val mutant of human transforming growth factor alpha (TGF-alpha) was reassigned at pH = 6.3. The conformation space of des-Val-Val TGF-alpha was explored by distance geometry embedding followed by restrained molecular dynamics refinement using NOE distan...

Topics

Computer Simulation
Humans
Hydrogen
Magnetic Resonance Spectroscopy
Models, Molecular
Mutation
Protein Conformation
Solutions
Stereoisomerism
Transforming Growth Factor alpha

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 2261437
DOI: 10.1021/bi00486a005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2261437-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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