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Article

The solution structure of heregulin-alpha and a N-terminal mutant with suppressed activity.

Biochemical and biophysical research communications - 5 Mar 1999

Adler M, Thompson S A

Abstract excerpt

NMR spectroscopy is used to compare the structure of the EGF-like domain of heregulin-alpha and HT1, a mutated form of heregulin-alpha with significantly reduced activity. HT1 is a chimeric protein that has the first seven residues of transforming growth factor-alpha and the sequence of heregulin-alpha from the first cysteine through the next 58 residues. The results demonstrate that both proteins share the same...

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Source

Identifiers

PMID: 10066440
DOI: 10.1006/bbrc.1998.9437

Genes

EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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