Article
Solution structure of the transforming growth factor beta-binding protein-like module, a domain associated with matrix fibrils.
The EMBO journal - 17 Nov 1997
Yuan X, Downing A K, Knott V, Handford P A
Abstract excerpt
Here we describe the high resolution nuclear magnetic resonance (NMR) structure of a transforming growth factor beta (TGF-beta)-binding protein-like (TB) domain, which comes from human fibrillin-1, the protein defective in the Marfan syndrome (MFS). This domain is found in fibrillins and latent T...
Topics
- Amino Acid Sequence
- Cell Adhesion
- Extracellular Matrix
- Fibrillin-1
- Fibrillins
- Humans
- Marfan Syndrome
- Microfilament Proteins
- Models, Molecular
- Molecular Sequence Data
- Mutation
- Nuclear Magnetic Resonance, Biomolecular
- Peptide Fragments
- Protein Structure, Secondary
- Protein Structure, Tertiary
- Recombinant Proteins
- Sequence Homology, Amino Acid
- Solutions