Article
Using mice to unveil the genetics of cancer resistance.
Biochimica et biophysica acta - 1 Dec 2012
van der Weyden Louise, Adams David J
Abstract excerpt
In the UK, four in ten people will develop some form of cancer during their lifetime, with an individual's relative risk depending on many factors, including age, lifestyle and genetic make-up. Much research has gone into identifying the genes that are mutated in tumorigenesis with the overwhelming majority of genetically-modified (GM) mice in cancer research showing accelerated tumorigenesis or recapitulating...
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