Article
Forty years of cancer modelling in the mouse.
European journal of cancer (Oxford, England : 1990) - 1 Sept 2004
Hirst G L, Balmain A
Abstract excerpt
Mouse models of human cancer have played an important role in formulating modern concepts of multistage carcinogenesis, and are providing us with a new armoury of tools for the testing of novel therapeutic approaches to cancer treatment. The development of inducible and conditional technologies provide us with greater opportunity to generate mouse models which faithfully recapitulate human tumorigenesis, in terms...
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