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Article

Frequency and genetic characterization of V(DD)J recombinants in the human peripheral blood antibody repertoire.

Immunology - 1 Sept 2012

Briney Bryan S, Willis Jordan R, Hicar Mark D, Thomas James W, Crowe James E

Abstract excerpt

Antibody heavy-chain recombination that results in the incorporation of multiple diversity (D) genes, although uncommon, contributes substantially to the diversity of the human antibody repertoire. Such recombination allows the generation of heavy chain complementarity determining region 3 (HCDR3) regions of extreme length and enables junctional regions that, because of the nucleotide bias of N-addition regions,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22612413
DOI: 10.1111/j.1365-2567.2012.03605.x
PMCID: PMC3449247

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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