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Article

Critical role of P1-Runx1 in mouse basophil development.

Blood - 5 Jul 2012

Mukai Kaori, BenBarak Maya J, Tachibana Masashi, Nishida Keigo, Karasuyama Hajime, Taniuchi Ichiro, Galli Stephen J

Abstract excerpt

Runx1(P1N/P1N) mice are deficient in the transcription factor distal promoter-derived Runt-related transcription factor 1 (P1-Runx1) and have a > 90% reduction in the numbers of basophils in the BM, spleen, and blood. In contrast, Runx1(P1N/P1N) mice have normal numbers of the other granulocytes...

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Source

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Identifiers

PMID: 22611151
DOI: 10.1182/blood-2011-12-399113
PMCID: PMC3390962

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22611151-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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