Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

EGFR array: uses in the detection of plasma EGFR mutations in non-small cell lung cancer patients.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Jul 2012

Yam Irene, Lam David Chi-Leung, Chan Kaimin, Chung-Man Ho James, Ip Mary, Lam Wah-Kit, Chan Tai-Kwong, Chan Vivian

Abstract excerpt

INTRODUCTION: We aim to develop a simple and sensitive array-based method for the detection of epidermal growth factor receptor (EGFR) gene mutations in the plasma of non-small-cell lung cancer patients and determine its use in the follow-up of those on tyrosine-kinase inhibitor (TKI) therapy. METHOD: DNA from 100 μl of plasma was amplified in the presence of peptide nucleic acid clamp to provide single-stranded...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Carcinoma, Non-Small-Cell Lung

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Squamous Cell

Share to DNA, Neoplasm

Share to Drug Resistance, Neoplasm

Share to Longitudinal Studies

Share to Protein Kinase Inhibitors

Share to Small Cell Lung Carcinoma

Source

Identifiers

PMID: 22610259
DOI: 10.1097/JTO.0b013e3182558198

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

EGFR array: uses in the detection of plasma EGFR mutations in non-small cell lung cancer patients.PMID 22610259Read ↗

Plasma EGFR Mutation Detection Associated With Survival Outcomes in Advanced-Stage Lung Cancer.Semantic proximity Read ↗

Detection of EGFR mutations using target capture sequencing in plasma of patients with non-small-cell lung cancerSemantic proximity Read ↗

Detection of mutations in EGFR in circulating lung-cancer cells.Semantic proximity Read ↗

Targeted Sequencing of Circulating Cell Free DNA Can Be Used to Monitor Therapeutic Efficacy of Tyrosine Kinase Inhibitors in Non-small Cell Lung Cancer Patients.Semantic proximity Read ↗

Detection of EGFR mutations in plasma and biopsies from non-small cell lung cancer patients by allele-specific PCR assays.Semantic proximity Read ↗

Detection of EGFR mutations in plasma DNA from lung cancer patients by mass spectrometry genotyping is predictive of tumor EGFR status and response to EGFR inhibitors.Semantic proximity Read ↗

Dynamics of EGFR Mutation Load in Plasma for Prediction of Treatment Response and Disease Progression in Patients With EGFR-Mutant Lung Adenocarcinoma.Semantic proximity Read ↗

Dynamic plasma EGFR mutation status as a predictor of EGFR-TKI efficacy in patients with EGFR-mutant lung adenocarcinoma.Semantic proximity Read ↗

Mutation analysis of circulating plasma DNA to determine response to EGFR tyrosine kinase inhibitor therapy of lung adenocarcinoma patients.Semantic proximity Read ↗

An evaluation study of EGFR mutation tests utilized for non-small-cell lung cancer in the diagnostic setting.Semantic proximity Read ↗

Genetic profiling and epidermal growth factor receptor-directed therapy in nonsmall cell lung cancer.Semantic proximity Read ↗

Non-invasive detection of EGFR deletion at exon 19 in non-small cell lung cancer by real time diagnostic.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.