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Detection of EGFR mutations using target capture sequencing in plasma of patients with non-small-cell lung cancer

20 Feb 2019

Abstract excerpt

Purpose Circulating tumour DNA (ctDNA) is a promising biomarker for detection of non-invasive epidermal growth factor receptor (EGFR ) mutations in patients with non-small-cell lung cancer (NSCLC). However, the existing methods have limitations in sensitivity or in availability. The aim was to evaluate the accuracy of capture target sequencing for detecting EGFR mutations in ctDNA. Methods A total of 79 patients...

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PMID: 30787028
DOI: 10.1136/jclinpath-2019-205699

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