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Article

Single-CpG-resolution methylome analysis identifies clinicopathologically aggressive CpG island methylator phenotype clear cell renal cell carcinomas.

Carcinogenesis - 1 Aug 2012

Arai Eri, Chiku Suenori, Mori Taisuke, Gotoh Masahiro, Nakagawa Tohru, Fujimoto Hiroyuki, Kanai Yae

Abstract excerpt

To clarify the significance of DNA methylation alterations during renal carcinogenesis, methylome analysis using single-CpG-resolution Infinium array was performed on 29 normal renal cortex tissue (C) samples, 107 non-cancerous renal cortex tissue (N) samples obtained from patients with clear cell renal cell carcinomas (RCCs) and 109 tumorous tissue (T) samples. DNA methylation levels at 4830 CpG sites were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22610075
DOI: 10.1093/carcin/bgs177
PMCID: PMC3418891

Genes

ASCL2
GRM6
KCNQ1
KHDRBS2
PCDHAC1
RIMS4
TRH
ZFP42

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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