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High-throughput methylation sequencing reveals novel biomarkers for the early detection of renal cell carcinoma

16 Jan 2025

Abstract excerpt

PURPOSE: Renal cell carcinoma (RCC) is a common malignancy, with patients frequently diagnosed at an advanced stage due to the absence of sufficiently sensitive detection technologies, significantly compromising patient survival and quality of life. Advances in cell-free DNA (cfDNA) methylation profiling using liquid biopsies offer a promising non-invasive diagnostic option, but robust biomarkers for early...

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PMID: 39819319
DOI: 10.1186/s12885-024-13380-6

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