Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DNA analysis of HLA-DR, DQ and DP genes in pauciarticular juvenile rheumatoid arthritis.

The Journal of rheumatology - 1 Nov 1991

Barron K S, Joseph A K, Macleod M, Gonzales J C, Owerbach D, Reveille J D

Abstract excerpt

HLA-DR, DQ, and DP alleles were determined by restriction fragment length polymorphism (RFLP) and oligonucleotide hybridization analysis in 50 Caucasian children with pauciarticular juvenile rheumatoid arthritis (PaJRA) and 82 controls. There was an increased frequency of DR5, DRw8, and DQw4, as well as individual DQ alpha and beta chains, DQA*0401 and DQB1*0402, respectively, in this group of patients. There was...

Topics

Alleles
Arthritis, Juvenile
Base Sequence
DNA
Genes
HLA-DP Antigens
HLA-DQ Antigens
HLA-DR Antigens
Humans
Molecular Sequence Data
Oligonucleotide Probes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Restriction Fragment Length

Reference Values

Source

Identifiers

PMID: 1686281

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1686281-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DNA analysis of HLA-DR, DQ and DP genes in pauciarticular juvenile rheumatoid arthritis.PMID 1686281Read ↗

DNA analysis of HLA-DR, DQ, and DP alleles in children with polyarticular juvenile rheumatoid arthritis.Semantic proximity Read ↗

HLA antigens in juvenile arthritis. Pauciarticular and polyarticular juvenile arthritis are immunogenetically distinct.Semantic proximity Read ↗

A distinct HLA-DRw8 haplotype characterizes patients with juvenile rheumatoid arthritis.Semantic proximity Read ↗

Immunogenetics of rheumatoid arthritis and juvenile arthritis.Semantic proximity Read ↗

The immunogenetics of juvenile rheumatoid arthritis.Semantic proximity Read ↗

HLA-DPB1*0301 is a major risk factor for rheumatoid factor-negative adult rheumatoid arthritis.Semantic proximity Read ↗

HLA class II alleles and heterogeneity of juvenile rheumatoid arthritis. DRB1*0101 may define a novel subset of the disease.Semantic proximity Read ↗

HLA-DP/DR interaction in early onset pauciarticular juvenile chronic arthritis.Semantic proximity Read ↗

Analysis of the HLA-DR gene frequencies in Japanese cases of juveniles rheumatoid arthritis and rheumatoid arthritis by oligonucleotide DNA typing.Semantic proximity Read ↗

HLA and juvenile rheumatoid arthritis.Semantic proximity Read ↗

Immunogenetics of juvenile chronic arthritis. I. HLA interaction between A2, DR5/8-DR/DQ, and DPB1*0201 is a general feature of all subsets of early onset pauciarticular juvenile chronic arthritis II. DPB1 polymorphism plays a role in systemic juvenile chronic arthritis.Semantic proximity Read ↗

HLA DPB1 alleles and susceptibility to rheumatoid arthritis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.