Article
Possible impact of ADRB3 Trp64Arg polymorphism on BMI in patients with schizophrenia.
Progress in neuro-psychopharmacology & biological psychiatry - 7 Aug 2012
Sasayama Daimei, Hori Hiroaki, Teraishi Toshiya, Hattori Kotaro, Ota Miho, Tatsumi Masahiko, Higuchi Teruhiko, Amano Naoji, Kunugi Hiroshi
Abstract excerpt
BACKGROUND: The β3-adrenoceptor (ADRB3) gene Trp64Arg polymorphism has been shown to be associated with obesity as well as type 2 diabetes and cardiovascular disease. The incidence of overweight and the risks of type 2 diabetes and cardiovascular disease are also increased in major depression and schizophrenia. We hypothesized that the Trp64Arg polymorphism may be associated with increased risk of schizophrenia...
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