Article
Metabolic syndrome and ADRB3 gene polymorphism in severely obese patients from South Italy.
European journal of clinical nutrition - 1 Oct 2007
Bracale R, Pasanisi F, Labruna G, Finelli C, Nardelli C, Buono P, Salvatori G, Sacchetti L, Contaldo F, Oriani G
Abstract excerpt
OBJECTIVE: To evaluate the prevalence of beta(3)-adrenergic receptor (ADRB3) Trp64Arg polymorphism and its relationship with the metabolic syndrome in severe obesity. DESIGN: Cross-sectional outpatients study. PATIENTS AND METHODS: In 265 (100 men) severely obese non-diabetic subjects and 78 (25 men) healthy volunteers, genomic DNA was isolated from peripheral leukocytes. In obese patients, plasma concentrations...
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