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Article

The mutational landscape of human olfactory G protein-coupled receptors.

BMC biology - 5 Feb 2021

Jimenez Ramón Cierco, Casajuana-Martin Nil, García-Recio Adrián, Alcántara Lidia, Pardo Leonardo, Campillo Mercedes, Gonzalez Angel

Abstract excerpt

BACKGROUND: Olfactory receptors (ORs) constitute a large family of sensory proteins that enable us to recognize a wide range of chemical volatiles in the environment. By contrast to the extensive information about human olfactory thresholds for thousands of odorants, studies of the genetic influence on olfaction are limited to a few examples. To annotate on a broad scale the impact of mutations at the structural...

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Identifiers

PMID: 33546694
DOI: 10.1186/s12915-021-00962-0
PMCID: PMC7866472

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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