Article
Pharmacogenetics of statins: achievements, whole-genome analyses and future perspectives.
Pharmacogenomics - 1 May 2012
Postmus Iris, Verschuren Jeffrey J W, de Craen Anton J M, Slagboom P Eline, Westendorp Rudi G J, Jukema J Wouter, Trompet Stella
Abstract excerpt
Statins are the most commonly prescribed class of drug worldwide and therapy is highly effective in reducing low-density lipoprotein cholesterol levels and cardiovascular events. However, there is large variability in clinical response to statin treatment. Recent research provides evidence that genetic variation contributes to this variable response to statin treatment. Until recently, pharmacogenetic studies...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.