Article
Association of genetic polymorphisms with response to bevacizumab for neovascular age-related macular degeneration in the Chinese population.
Pharmacogenomics - 1 May 2012
Tian Jun, Qin Xueying, Fang Kai, Chen Qing, Hou Jing, Li Juan, Yu Wenzhen, Chen Dafang, Hu Yonghua, Li Xiaoxin
Abstract excerpt
AIMS: To determine whether there is an association between CFH, ARMS2, HTRA1, VEGF, SERPING1 or C3 genotypes and patient response to treatment with intravitreal bevacizumab for neovascular age-related macular degeneration (AMD). MATERIALS & METHODS: This was a multicenter prospective study. One hundred and forty four patients with neovascular AMD treated with bevacizumab were recruited from 13 centers. Twelve...
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