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Article

p16/Ki-67 dual staining has a better accuracy than human papillomavirus (HPV) testing in women with abnormal cytology under 30 years old.

Bosnian journal of basic medical sciences - 8 Nov 2019

Pirtea Laurențiu, Secosan Cristina, Margan Madalin, Moleriu Lavinia, Balint Oana, Grigoras Dorin, Sas Ioan, Horhat Florin, Jianu Adelina, Ilina Răzvan

Abstract excerpt

Due to a high rate of transient human papillomavirus (HPV) infection, HPV genotyping has a low specificity for high-grade cervical lesions, especially in young women. p16/Ki-67 dual immunocytochemical staining can also be used for the detection of oncogenic changes in cervical cells. Our aim was to compare the performance of p16/Ki-67 dual staining and HPV genotyping in the detection of high-grade cervical...

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Identifiers

PMID: 29924960
DOI: 10.17305/bjbms.2018.3560
PMCID: PMC6868483

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IVD

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