Article
The importance of combined HPV and CINtec® PLUS genotyping testing for p16 in women with cervical squamous cell carcinoma.
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie - 1 Jan 2000
Voidăzan Toader Septimiu, Budianu Mihaela Alexandra, Cotoi Ovidiu Simion, Turdean Sabin Gligore
Abstract excerpt
INTRODUCTION: Immunohistochemistry (IHC) for p16INK4A (p16) is a reliable surrogate test for the presence of a high-risk, potentially transformative human papillomavirus (HPV) infection in precursor and malignant lesions of the cervix. The purpose of this study was to evaluate changes in cervical cells caused by persistent HPV infection, by IHC (p16 protein) by comparison with HPV genotyping. PATIENTS, MATERIALS...
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