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Article

Interleukin-18 and interferon-γ single nucleotide polymorphisms in Egyptian patients with tuberculosis.

PloS one - 1 Jan 2021

Hassuna Noha A, El Feky Mohamed, Hussein Aliae A R Mohamed, Mahmoud Manal A, Idriss Naglaa K, Abdelwahab Sayed F, Ibrahim Maggie A

Abstract excerpt

BACKGROUND: Interleukin-18 (IL-18) and interferon-γ (IFN-γ) are cytokines of crucial role in inflammation and immune reactions. There is a growing evidence supporting important roles for IL-18 and IFN γ in tuberculosis (TB) infection and anti-tuberculosis immunity. OBJECTIVE: To evaluate the role of polymorphisms in IL-18-607 and -137 and INF-γ +874 in susceptibility to TB infection among Egyptian patients....

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Identifiers

PMID: 33412574
DOI: 10.1371/journal.pone.0244949
PMCID: PMC7790531

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