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Article

Factors influencing inadequate or suboptimal response to adefovir with or without genotypic resistance.

Journal of medical virology - 1 Jul 2012

Zhou Xia, Kuang XueMei, Fan Ke, Zhang ChangJiang, Deng GuoHong, Wang HuiFen, Wang YuMing

Abstract excerpt

The aim of the study was to explore the factors in inadequate-responders to treatment with adefovir (ADV) with or without genotypic resistance. The reverse-transcriptase (RT) gene of hepatitis B virus (HBV) was sequenced in 161 patients with inadequate-response to ADV and analyzed for HBV genotypes using a phylogenetic approach. Seventy-six patients (47.2%) were found to carry the rtA181V/T/S or rtN236T residue...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22585719
DOI: 10.1002/jmv.23270

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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