Article
Genetic variants of CDH23 associated with noise-induced hearing loss.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology - 1 Feb 2014
Kowalski Tomasz Jarema, Pawelczyk Malgorzata, Rajkowska Elzbieta, Dudarewicz Adam, Sliwinska-Kowalska Mariola
Abstract excerpt
OBJECTIVES: Noise-induced hearing loss (NIHL) is a complex disease resulting from the interaction between external and intrinsic/genetic factors. Based on mice studies, one of the most interesting candidate gene for NIHL susceptibility is CDH23-encoding cadherin 23, a component of the stereocilia tip links. The aim of this study was to analyze selected CDH23 single nucleotide polymorphisms (SNPs) and to evaluate...
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