Article
Association between in vivo alcohol metabolism and genetic variation in pathways that metabolize the carbon skeleton of ethanol and NADH reoxidation in the alcohol challenge twin study.
Alcoholism, clinical and experimental research - 1 Dec 2012
Lind Penelope A, Macgregor Stuart, Heath Andrew C, Madden Pamela A F, Montgomery Grant W, Martin Nicholas G, Whitfield John B
Abstract excerpt
BACKGROUND: Variation in alcohol metabolism affects the duration of intoxication and alcohol use. While the majority of genetic association studies investigating variation in alcohol metabolism have focused on polymorphisms in alcohol or aldehyde dehydrogenases, we have now tested for association with genes in alternative metabolic pathways that catalyze the carbon skeleton of ethanol (EtOH) and NADH reoxidation....
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